SOD1 anticorps

N° du produit ABIN180961

Cet anticorps Souris Monoclonal détecte spécifiquement SOD1 dans IHC (p), IHC (fro) et EIA. Il présente une réactivité envers Humain, Souris et Boeuf (Vache).

Aperçu rapide pour SOD1 anticorps (ABIN180961)

Antigène: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Reactivité: Humain, Souris, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOD1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: 2F5

Détail du produit anti-SOD1 anticorps

Specificité: This antibody recognizes Copper/Zinc Superoxide Dismutase (SOD). It does not cross react with immunoglobulins but does react weakly with Mn SOD.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Human.
Species reactivity (tested):Bovine.

Attributs du produit: Synonyms: SOD-1, CuZn-SOD, CuZnSOD, IPOA, ALS1, Superoxide dismutase [Cu-Zn]

Purification: Affinity Chromatography on Protein G

Immunogène: Superoxide dismutase enzyme prepared from bovine erythrocytes. Cells from immunisedmice were fused with cells of the mouse Sp-2/0-Ag14 myeloma cell line.

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: This product does not require pre-treatmentof paraffin embedded sections e. g. trypsin or pronase prior to staining. This product doesnot require antigen retrieval using heat treatment methods prior to staining of paraffinsections. Recommended Positive Control: Human spleen and lymph node.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative and 0.1 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur SOD1

Antigène: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Autre désignation: Superoxide Dismutase 1 / SOD1

Sujet: Superoxide dismutases are ubiquitous metalloproteins that destroy oxygen-mediated free radicals, that are normally produced within the cells, which are toxic to biological systems. There are three forms of superoxide dismutase, including the Fe, mitochondrial (Mn) and the copper/zinc binding (Cu/Zn) form. The Cu/Zn form of SOD is utilised by most eukaryotic organisms. SOD Cu/Zn prevents oxygen-mediated free radical damage by catalysing the dismutation of the toxic superoxide radical to molecular oxygen and hydrogen peroxide. Superoxide dismutatses catalyzes the conversion of single electron reduced species of molecular oxygen to hydrogen peroxide and oxygen. Cu, Zn superoxide dismutase (SOD1) is widely distributed and comprises 90 % of total SOD. Mutations in SOD1 cause a form of familial ALS. Oxidative modifications and aggregation of SOD1 has been associated with Alzheimer's and Parkinson's disease.Synonyms: ALS1, CuZn-SOD, CuZnSOD, IPOA, SOD-1, Superoxide dismutase [Cu-Zn]

ID gène: 6647

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis